Bacterial Diversity and Their Antimicrobial Susceptibility Patterns in Diabetic Foot Infections, a Tertiary Care Hospital Study

Abstract

Objective: To determine the frequency of bacterial pathogens and their antimicrobial profile in diabetic foot
infections.
Study Design: Cross-sectional study.
Place and Duration of Study: The study was conducted at the Department of Microbiology, Combined Military
Hospital (CMH) Lahore, Pakistan from January 2022 to December 2022.
Methods: Three hundred and forty-one samples with a history of diabetic foot infections were processed.
Antibiotic susceptibility testing was done using the Kirby-Bauer Disk Diffusion technique for the commonly
used antibiotics. Clinical and Laboratory Standard Institute Guidelines (CLSI) 2022 were used to interpret the
result of susceptibility testing.
Results: Three hundred and forty-one clinical samples with bacterial isolates causing diabetic foot infections
were processed. The most common organism isolated was Pseudomonas aeruginosa (25.5%). Gram-positive
isolates where found most susceptible to vancomycin and linezolid while gram negative was most sensitive to
meropenem.
Conclusion: In the current study gram-negative bacteria were found to be the main pathogens. Effective
antibiotic therapy based on microbiological profiles will definitely improve clinical outcomes.

How to cite this: Hussain C, Farooque MA, Ain Q, Khan SH, Younas A, Huma Z. Bacterial Diversity and Their Antimicrobial Susceptibility Patterns in Diabetic Foot Infections, a Tertiary Care Hospital Study. Life and Science. 2024; 5(4): 433-438. doi: http://doi.org/10.37185/LnS.1.1.633