Evaluation of Restless Leg Syndrome in Patients with Non-Dialysis Dependent Chronic Kidney Disease at Fatima Memorial Hospital Lahore: A Cross-sectional Study

Abstract

Objective: To determine the occurrence of restless leg syndrome in individuals with non-dialysis-dependent
chronic kidney disease.
Study Design: A descriptive cross-sectional study.
Place and Duration of Study: The study was carried out at the Outpatient Department (OPD) of Fatima
Memorial Hospital, Lahore, Pakistan, from March 2020 to August 2020.
Methods: A total of 280 CKD patients not dependent on dialysis were included in the study. The data were
collected through interviews containing questions from international restless leg syndrome study group
(IRLSSG). Patients were stratified into different stages according to the estimated glomerular filtration rate
(eGFR). Restless leg syndrome was diagnosed by analyzing the responses of the interview marked by the
examiner.
Results: Among 280 patients, 15.7% (n=44) of chronic kidney disease patients were noted to have restless leg
syndrome. The syndrome was significantly more frequent in females and was associated with higher CKD stages (Stage V > Stage III and IV). There was no association with either age or BMI.
Conclusion: Restless leg syndrome is more common in chronic kidney disease stage V as compared to lower
chronic kidney disease stages (III & IV). If untreated, it can affect patients' quality of life and increase the risk of
cardiovascular activities.

How to cite this: Basit MB, Sabir O, Shahid AH, Kanwal A, Qadri GA, Rizvi N. Evaluation of Restless Leg Syndrome in Patients with NonDialysis Dependent Chronic Kidney Disease at Fatima Memorial Hospital Lahore: A Cross-sectional study. Life and Science. 2024; 5(1): 95-100.doi: http://doi.org/10.37185/LnS.1.1.516