Intracranial Spread of Infections Among the Patients of Chronic Suppurative Otitis  Media

Muhammad Imran Malik; Aiman Fatima Naqvi; Syeda Uzma Naqvi; Nida Khan; Aijaz Ali; Najaf Abbas

doi:10.37185/LnS.1.1.476

Muhammad Imran Malik Fazaia Medical College PAF Hospital, Islamabad, Pakistan
Aiman Fatima Naqvi Karachi Institute of Medical Sciences (KIMS), Combined Military Hospital (CMH), Malir Cantt Karachi, Pakistan
Syeda Uzma Naqvi Dow University of Health and Sciences, Karachi, Pakistan
Nida Khan Mohtarma Benazir Bhutto Shaheed Medical College, Karachi, Pakistan
Aijaz Ali Dow University of Health and Sciences, Karachi, Pakistan
Najaf Abbas FMH College of Medicine & Dentistry, Lahore, Pakistan

DOI: https://doi.org/10.37185/LnS.1.1.476

Keywords: Chronic Suppurative Otitis Media, Complication, Intracranial Spread of Infections, Middle Ear, Routes, Sites

Abstract

Objective: To determine the frequency of intracranial spread of infections among the patients of chronic
suppurative otitis media presenting at a tertiary care hospital in Karachi.
Study Design: Cross-Sectional Study.
Place and Duration of Study: The study was carried out at the Department of ENT, Head and Neck Surgery, Dow Medical College, Dr. K.M Ruth Pfau Civil Hospital, Karachi, Pakistan, from January 2021 to January 2022.
Methods: Out of 87 patients with Chronic Suppurative Otitis Media were included using a non-probability
sampling technique. Possible routes of spread of infections were identified based on per operative findings. The
Descriptive statistics were applied to all parameters. On inferential statistics, Chi-square test was used for
stratification, considering p-value ≤0.05 as significant.
Results: 75 (86.2%) were male and 12 (13.8%) were female. 21 (24.1%) patients were found with meningitis, 11
(12.6%) with lateral sinus thrombosis, and 2 (2.3%) with otitis hydrocephalus. As far as signs and symptoms are
concerned, 87 (100%) patients had a headache, 74 (85.1%) had nausea and vomiting, 44 (50.6%) patients had
vertigo, 43 (49.4%) had a fever, 18 (20.7%) had diplopia, and 73 (83.9%) had altered consciousness. 69 (79.3%)
of patients' route of infection in the patients of chronic suppurative otitis media had bone erosion, 12 (13.8%)
had thrombophlebitis, and 6 (6.9%) had anatomical pathways. Among different sites of spread of infection, the
most common site was sinodural angle 45 (51.72%).
Conclusion: Bone erosion, with 79.3%, was the most prevalent route of intracranial spread, followed by
thrombophlebitis and anatomical pathways.

How to cite this: Malik MI, Naqvi AF, Naqvi SU, Khan N, Ali A, Abbas N. Routes and Sites of Intracranial Spread of Infections Among the Patients of Chronic Suppurative Otitis Media. Life and Science.2023; 4(4): 476-482. doi: http://doi.org/10.37185/LnS.1.1.476