Correlation of Total Leucocyte Count, Neutrophil to Lymphocyte Ratio and Platelet Count with Duration of Hospital Stay in Dengue Fever

Abstract

Objective: To assess the correlation of total leucocyte count (TLC), neutrophil to lymphocyte ratio (NLR), and platelet count with the duration of hospital stay in dengue patients.
Study Design: A cross-sectional study.
Place and Duration of Study: The study was conducted at the Department of Haematology and Dengue Ward, Pak Emirates Military Hospital (PEMH) Rawalpindi, Pakistan from January 2023 to February 2023.
Methods: Comprised 136 confirmed dengue-positive patients who were admitted to PEMH with symptoms of fever. All the participants were requested for their informed consent before their enrolment in the study. A 3 ml venous sample was taken, and complete blood counts were determined by Sysmex XN-3000.TLC, Hematocrit, platelet count, and differentials were measured while Neutrophil the neutrophil-to-lymphocyte ratio was calculated. Patients were followed in hospital and their total hospital stay was noted. Correlation of total leucocyte count, neutrophil to lymphocyte ratio, and platelet count in dengue patients with duration of hospital stay was noted.
Results: TLC and the neutrophil-to-lymphocyte ratio did not show any significant correlation with hospital stay in dengue patients. However, platelet count was found to be negatively correlated with hospital stay duration (r = -0.864, P = 0.00).
Conclusion: Platelet count has a significant negative correlation with hospital stay in dengue patients and is found to be a good predicting factor for indoor stay of dengue patients.

How to cite this: Sajjad Z, Tashfeen S, Shahid S, Bibi A, Irfan R, Naeem U, Butt MN. Correlation of Total Leucocyte Count, Neutrophil to Lymphocyte Ratio and Platelet Count with Duration of Hospital Stay in Dengue Fever. Life and Science. 2025; 6(1): 15-20. doi: http://doi.org/10.37185/LnS.1.1.466