Gestational Diabetes Mellitus (GDM) Related Common Risk Factors and Recurrence among Pregnant Patients: A Multifactorial Cross-Sectional Study
Abstract
Objective: To determine the frequency of newly diagnosed gestational diabetes mellitus (GDM) and common associated factors in recurrent GDM.
Study Design: Cross sectional.
Place and Duration of Study: The study was conducted in the department of Obstetrics and Gynecology unit A of Lady Reading Hospital, Peshawar from 27th July 2016 to 27th Jan 2017.
Materials and Methods: 336 women meeting the eligibility criteria (18-45 years, of any gestational age with gestational diabetes mellitus history and diagnosed as recurrent gestational diabetes) were included in the study. All patients who were labeled as a case of recurrent gestational diabetes was further investigated for any risk factor associated with its recurrence.
Results: The recurrence of Gestational Diabetes was observed in 99 (29.46%) patients, in which 77% of patients had family history positive.
Conclusion: Keeping in view the recurrence of gestational diabetes proper screening and medical care for GDM in women during the childbearing years is highly recommended.
References
Kampmann U, Madsen LR, Skajaa GO, Iversen DS, Moeller N, Ovesen P. Gestational diabetes: a clinical update. World journal of diabetes. 2015; 6: 1065.
Kim C. Maternal outcomes and follow-up after gestational diabetes mellitus. Diabet Med. 2014; 31: 292-01.
Rayanagoudar G, Hashi AA, Zamora J, Khan KS, Hitman GA, Thangaratinam S. Quantification of the type 2 diabetes risk in women with gestational diabetes: a systematic review and meta-analysis of 95,750 women. 2016; 59:1403–11.
Zhu Y, Zhang C. Prevalence of gestational diabetes and risk of progression to type 2 diabetes: a global perspective. Curr Diab Rep. 2016; 16: 7.
Kruse AR, Darling MS, Hansen MKL, Markman MJ, Lauszus FF, Wieland HB. Recurrence of gestational diabetes in primiparous women. acta obstet gynecol scand. 2015; 94; 1367-72.
Duman NB.Frequency of gestational diabetes mellitus and the associated risk factors. Pak JMed Sci. 2015; 31: 194-7.
Schwartz N, Green MS, Yefet E, Nachum Z. Modifiable risk factors for gestational diabetes recurrence. Endocrine. 2016; 54: 714–22.
Schoenaker DA, Soedamah-Muthu SS, Callaway LK, Mishra GD. Pre-pregnancy dietary patterns and risk of gestational diabetes mellitus: results from an Australian population- based prospective cohort study. Diabetologia. 2015; 58: 2726-35.
Kruse AR, Darling MS, Hansen MK, Markman MJ, Lauszus FF, Wielandt HB. Recurrence of gestational diabetes in primiparous women. Acta obstetricia et gynecologica Scandinavica. 2015; 94: 1367-72.
Schwartz N, Nachum Z, Green MS. The prevalence of gestational diabetes mellitus recurrence—effect of ethnicity and parity: a metaanalysis. American journal of obstetrics and gynecology. 2015; 213: 310-7.
Basit A, Fawwad A, Qureshi H, Shera AS & NDSP Members. Prevalence of diabetes, pre-diabetes and associated risk factors: second National Diabetes Survey of Pakistan (NDSP), 2016-2017. BMJ. 2018; 8: e020961.
Aamir AH, Ul-Haq Z, Mahar SA, Qureshi FM, Ahmad I, Jawa A, et al. Diabetes Prevalence Survey of Pakistan (DPS-PAK): prevalence of type 2 diabetes mellitus and prediabetes using HbA1c: a population-based survey from Pakistan. BMJ Open. 2019; 9: e025300.
Wang YY, Liu Y, Li C, Lin J, Liu XM, Sheng JZ, et al. Frequency and risk factors for recurrent gestational diabetes mellitus in primiparous women: a case control study. BMC endocrine disorders. 2019; 19: 1-7.
Riaz M, Nawaz A, Masood SN, Fawwad A, Basit A, Shera AS. Frequency of gestational diabetes mellitus using DIPSI criteria, a study from Pakistan. Clinical Epidemiology and Global Health. 2019; 7: 218-21.
Rottenstreich M, Rotem R, Reichman O, Farkash R, Rottenstreich A, Samueloff A, et al. Previous non-diabetic pregnancy with a macrosomic infant - Is it a risk factor for subsequent gestational diabetes mellitus?. Diabetes Research Clinical Practice. 2020; 168: 108364.
Pu J, Zhao B, Wang EJ, Nimbal V, Osmundson S, Kunz L, et al. Racial/ethnic differences in gestational diabetes prevalence and contribution of common risk factors. Paediatric and perinatal epidemiology. 2015; 29: 436-43.
Chong YS, Cai S, Lin H, Soh SE, Lee YS, Leow MK, et al. Ethnic differences translate to inadequacy of high-risk screening for gestational diabetes mellitus in an Asian population: a cohort study. BMC pregnancy and childbirth. 2014; 14: 345.
Wang LF, Wang HJ, Ao D, Liu Z, Wang Y, Yang HX. Influence of pre-pregnancy obesity on the development of macrosomia and large for gestational age in women with or without gestational diabetes mellitus in Chinese population. Journal of Perinatology. 2015 ; 35: 985-90.
Wong VW, Lin A, Russell H. Adopting the new World Health Organization diagnostic criteria for gestational diabetes: How the prevalence changes in a high-risk region in Australia. Diabetes research and clinical practice. 2017; 129: 148-53.
Mukerji G, Kainth S, Pendrith C, Lowe J, Feig DS, Banerjee AT, et al. Predictors of low diabetes risk perception in a multi-ethnic cohort of women with gestational diabetes mellitus. Diabetic Medicine. 2016; 33: 1437-44.
Chang AL, Hurwitz E, Miyamura J, Kaneshiro B, Sentell T. Maternal risk factors and perinatal outcomes among pacific islander groups in Hawaii: a retrospective cohort study using statewide hospital data. BMC pregnancy and childbirth. 2015; 15: 239.
McDonald R, Karahalios A, Le T, Said J. A retrospective analysis of the relationship between ethnicity, body mass index, and the diagnosis of gestational diabetes in women attending an Australian antenatal clinic. International journal of endocrinology. 2015; 2015.
Nanditha A, Ma RC, Ramachandran A, Snehalatha C, Chan JC, Chia KS, et al. Diabetes in Asia and the Pacific: implications for the global epidemic. Diabetes care. 2016; 39: 472-85.
Yuen L, Wong VW. Gestational diabetes mellitus: challenges for different ethnic groups. World journal of diabetes. 2015; 6: 1024.
Lin PC, Hung CH, Chan TF, Lin KC, Hsu YY, Tzeng YL. The risk factors for gestational diabetes mellitus: a retrospective study. Midwifery. 2016; 42: 16-20.
Syngelaki A, Pastides A, Kotecha R, Wright A, Akolekar R, Nicolaides KH. First-trimester screening for gestational diabetes mellitus based on maternal characteristics and history. Fetal diagnosis and therapy. 2015; 38: 14-21.
Silva-Zolezzi I, Samuel TM, Spieldenner J. Maternal nutrition: opportunities in the prevention of gestational diabetes. Nutrition reviews. 2017; 75: 32-50.